Post-translational modifications of PRC2: signals directing its activity

Polycomb repressive complex 2 (PRC2) is a chromatin-modifying enzyme that catalyses the methylation of histone H3 at lysine 27 (H3K27me1/2/3). This complex maintains gene transcriptional repression and plays a...

Source: Epigenetics and Chromatin - October 31, 2020 Category: Genetics & Stem Cells Authors: Yiqi Yang and Gang Li Tags: Review Source Type: research