A novel RHD allele caused by c.739 G > C mutation was identified in a Chinese individual.

A novel RHD allele caused by c.739 G> C mutation was identified in a Chinese individual.
Transfusion. 2020 Oct 27;:
Authors: Lyu H, Jiao S, Ma W, Hu B
Abstract
The blood sample of a pregnant Chinese woman of the north Han population was confirmed as D variation by serologic method, and subsequent detection of RHD Exons 1 through 10 by the polymerase chain reaction-sequence-specific primer test showed that all exons were present. To further clarify the molecular mechanism of this sample, we sequenced the RHD Exons 1 through 10 and found that it was a novel allele caused by c.739 G> C in Exon 5.
PMID: 33107612 [PubMed - as supplied by publisher]

Source: Transfusion - October 27, 2020 Category: Hematology Authors: Lyu H, Jiao S, Ma W, Hu B Tags: Transfusion Source Type: research