Oncotarget: Sirolimus-eluting stents -- opposite in vitro effects on the clonogenic cell potential

(Impact Journals LLC) The cover for issue 31 of Oncotarget features Figure 4, " Concentration dose-response curves of sirolimus effect [55 nM-1 nM] on the number of cells per surviving colony in U2OS cell line after 2 weeks exposure, " by Vasuri, et al. which reported that the authors evaluated the long-term effects of sirolimus on three different cell in vitro models, cultured in physiological conditions mimicking sirolimus-eluted stent, in order to clarify the effectiveness of sirolimus in blocking cell proliferation and survival.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news