Prognostic Value of Multiparametric MRI-Based Radiomics model: Potential Role for Chemotherapeutic Benefits in Locally Advanced Rectal Cancer

Outcome for patients with locally advanced rectal cancer(LARC) has improved over past decades, in part because of the use of neoadjuvant chemoradiotherapy (NCRT) followed by total mesorectal excision(TME) surgery[1 –2]. The local recurrence(LR) rates has been dramaticallyreduced to less than 10%. Whereas, distant metastasis(DM) is remain the major cause of treatment failure in LARC[3–4]. Adjuvant chemotherapy(AC) has been recommended for LARC to reduce the incidence of DM. However, only certain subgroups o f patients could benefit from AC.

Source: Radiotherapy and Oncology - September 21, 2020 Category: Radiology Authors: Yanfen Cui, Wenhui Yang, Jialiang Ren, Dandan Li, Xiaosong Du, Junjie Zhang, Xiaotang Yang Tags: Original Article Source Type: research