Validation of the PLASMIC score for predicting ADAMTS13 activity < 10% in patients with suspected thrombotic thrombocytopenic purpura in Alberta, Canada
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy (TMA) that requires prompt plasma exchange. Clinical prediction tools may facilitate decision-making in institutions with delayed turnaround time or limited access to ADAMTS13 assays. The PLASMIC score and Bentley score have been shown to predict severe ADAMTS13 deficiency with excellent sensitivity and specificity.
Source: Thrombosis Research - Category: Hematology Authors: Chris Wynick, Joanne Britto, Daniel Sawler, Arabesque Parker, Mohammad Karkhaneh, M. Dawn Goodyear, Haowei (Linda) Sun Tags: Full Length Article Source Type: research