Epinephrine in Anaphylaxis: Too Little, Too Late Epinephrine in Anaphylaxis: Too Little, Too Late

Epinephrine is the recommended treatment for anaphylaxis, yet it is routinely underutilized among both patients and clinicians. What strategies may help increase the usage of this life-saving drug?Current Opinion in Allergy and Clinical Immunology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Allergy & Clinical Immunology Journal Article Source Type: news

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Publication date: Available online 28 September 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Roger J. Yu, Matthew S. Krantz, Elizabeth J. Phillips, Cosby A. Stone
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
The number of children showing up in emergency departments with anaphylaxis may spike during Halloween and Easter, a new study suggests.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news
Abstract The case involved a man in his forties. While working at the restaurant that the patient runs, the patient experienced a stab-like pain on the left shoulder and developed systemic pruritic eruptions. He was diagnosed with anaphylaxis upon visiting our emergency department. Conjunctival hyperemia, lip swelling, cold sweats, and nausea presented later. A cap fluorescence enzyme immunoassay using the serum of the patient showed specific immunoglobulin E (IgE) positivity for wasps; therefore, we hypothesized that he had anaphylaxis caused by the insect's sting. Insects of the same species as that by which the...
Source: Arerugi - Category: Allergy & Immunology Authors: Tags: Arerugi Source Type: research
Conclusions: Deaths from food-related anaphylaxis were rare; however, rates of hospitalization and ED visits increased. Prevention efforts related to peanut allergies among children should continue, and additional attention is needed to prevent and treat anaphylaxis among adults, particularly those with known crustacean allergies where case fatality is highest.
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: Research Reports Source Type: research
The incidence of hypersensitivity reactions (HSRs) to iodinated contrast media (ICM) has risen over last years, representing an important health problem. HSRs to ICMs are classified into immediate reactions (IRs) and non-immediate reactions (NIRs) according to if they occur within 1 h or longer after ICM administration. The diagnosis of HSRs to ICM is complex as skin test (ST) sensitivity ranges widely, and drug provocation test (DPT) protocols are heterogeneous. In this manuscript, we describe the clinical characteristics of a series of patients confirmed as HSR to ICM and the diagnosis procedure carried out, looking...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
This study has the potential to transform the diagnosis and treatment of allergic disorders.
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Mast cell (MC)-associated diseases, including allergy/anaphylaxis and neuroinflammatory pain disorders, exhibit a sex bias, with females at increase risk. While much attention has been directed toward adult sex hormones as drivers of sex differences, that female sex bias in MC-associated diseases is evident in prepubertal children, suggesting early-life origins of...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
A new study found that serious allergic reactions (anaphylaxis) triggered by peanuts jumped 85% when kids were trick or treating.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Conclusion: In the present study, NSAID cross-anaphylaxis was more frequent in women, and acetylsalicylic acid and dipyrone were the main triggers. Rhinitis was the main allergic comorbidity, and there was a high incidence of atopy. The majority tolerated selective COX-2 NSAIDs.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
MONDAY, Sept. 21, 2020 -- Parents of kids with food allergies probably won't be surprised to hear that Halloween is an especially risky time for their youngsters. A new study found that serious allergic reactions (anaphylaxis) triggered by peanuts...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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