[ASAP] Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c01086

Source: Journal of Medicinal Chemistry - September 9, 2020 Category: Chemistry Authors: Xiaohui Du, Jared Moore, Brian R. Blank, John Eksterowicz, Dena Sutimantanapi, Natalie Yuen, Todd Metzger, Brenda Chan, Tom Huang, Xi Chen, Yuping Chen, Frank Duong, Wayne Kong, Jae H. Chang, Jessica Sun, Tatiana Zavorotinskaya, Qiuping Ye, Melissa R. Jun Source Type: research