Dual-Phase 99mTc-MIBI SPECT/CT in the Characterization of Enhancing Solid Renal Tumors: A Single-Institution Study of 147 Cases

Purpose The aim of this study was to investigate the value of dual-phase 99mTc-MIBI SPECT/CT in the differential diagnosis between benign and malignant enhancing solid renal tumors. Patients and Methods Totally, 180 patients were imaged with dual-phase 99mTc-MIBI SPECT/CT, which was performed 30 minutes and 90 minutes after 99mTc-MIBI administration. Among them, 147 patients with 148 histologically proved solid renal tumors met the selection criteria and were included for the final analysis. Relative quantification was performed by measuring the radioactive uptake ratio of tumor to the normal renal parenchymal background for both early and delayed images. Results Benign renal tumors (4 renal oncocytomas and 8 lipid-poor angiomyolipomas) demonstrated a significantly higher early relative uptake value (ERUV) and delayed relative uptake value (DRUV) than malignant renal tumors (n = 136; both P
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research