Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model.

Design and manufacture of a coronary stent INC-1 and initial tests in experimental animal model. Arch Cardiol Mex. 2020;90(2):142-147 Authors: Abundes-Velasco A, Jiménez-Rodríguez GM, Romero-Ibarra JL, Sandoval-Jones JP, Sánchez-Pérez E, Galaz-Méndez R, Ulacia-Flores P, Farjat-Pasos JI, Padilla-Ibarra J, González SA, Martínez-Ríos MA, Peña-Duque MA, Rodriguez-Parra DA Abstract In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity,...
Source: Archivos de Cardiologia de Mexico - Category: Cardiology Authors: Tags: Arch Cardiol Mex Source Type: research