Radiological imaging features of the salivary glands in xerostomia induced by an immune checkpoint inhibitor

We report a case of a 56-year-old male patient diagnosed with ICI-induced xerostomia. The patien t underwent various imaging examinations to investigate the condition of the salivary glands, which indicated the following: (1) less specific findings on contrast-enhanced computed tomography, (2) mixed with intermediate and low signal intensity on bothT1-weighted and fat-suppressedT2-weighted magnetic resonance imaging and poor “salt and pepper” appearance on magnetic resonance sialography, and (3) multiple ovoid hypoechoic areas with hyperechoic bands without acute sialadenitis on ultrasound. These radiologic imaging findings suggested remarkable lymphocyte infiltration, which could be a characteristic of ICI-induced xerostomia.
Source: Oral Radiology - Category: Radiology Source Type: research