A serine loop in tissue factor mediates substrate selectivity by the tissue factor - factor VIIa complex.

CONCLUSIONS: Our results provide new insights into how the TF-FVIIa complex actively selects between its major protein substrates, which is mediated by a TF serine loop.
PMID: 32885882 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - September 3, 2020 Category: Hematology Authors: Birkle F, Morrissey JH Tags: J Thromb Haemost Source Type: research