[Endocrinological mechanisms in the pathophysiology of hidradenitis suppurativa].

[Endocrinological mechanisms in the pathophysiology of hidradenitis suppurativa]. Hautarzt. 2020 Sep 04;: Authors: Nikolakis G, Karagiannidis I, Vaiopoulos AG, Becker M, Zouboulis CC Abstract Hidradenitis suppurativa (HS) is a chronic, recurrent cutaneous disease of the terminal hair follicle which manifests with deep-seated, painful nodules, abscesses, and sinus tract formation. The pathophysiology of the disease includes among various factors also dermatoendocrinologic variables: Correlations with metabolic syndrome, obesity, sex steroid hormones, and the improvement after antiandrogen therapy are some of the key points presented in this review. Hormonal treatment of HS can be an effective and inexpensive alternative or add-on therapy to classic HS treatments, especially in cases where antibiotics and/or biologics are ineffective or contraindicated. PMID: 32886132 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research