Association between MRI histogram features and treatment response in locally advanced cervical cancer treated by chemoradiotherapy

ConclusionADC and T2W histogram features could be used to track changes in LACC tumours undergoing CCRT. Post-CCRT ADC50 was associated with treatment response with good observer repeatability.Key Points• Pre-treatment tumour delineation and histogram feature values had good observer repeatability, while these were less repeatable at post-treatment.• MRI histogram analysis could be used to track changes in the tumour as it undergoes concurrent chemoradiotherapy.• Post-treatment median ADC was associated with treatment response and had good repeatability.
Source: European Radiology - Category: Radiology Source Type: research