ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic

Acta Pharmacologica Sinica, Published online: 27 August 2020; doi:10.1038/s41401-020-00504-4ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic

Source: Acta Pharmacologica Sinica - August 26, 2020 Category: Drugs & Pharmacology Authors: Juan Wang Yu Zhang Wen-jing Huang Jun Yang Wei-guo Tang Tao-min Huang Wen-fu Tan Source Type: research