A report on DNA sequence determinants in gene expression.

A report on DNA sequence determinants in gene expression. Bioinformation. 2020;16(5):422-431 Authors: Singh R, Sophiarani Y Abstract The biased usage of nucleotides in coding sequence and its correlation with gene expression has been observed in several studies. A complex set of interactions between genes and other components of the expression system determine the amount of proteins produced from coding sequences. It is known that the elongation rate of polypeptide chain is affected by both codon usage bias and specific amino acid compositional constraints. Therefore, it is of interest to review local DNA-sequence elements and other positional as well as combinatorial constraints that play significant role in gene expression. PMID: 32831525 [PubMed - as supplied by publisher]
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research