On the Surface: Skin Microbial Exposure Contributes to Allergic Disease

Allergic disorders, characterized by IgE sensitivity, are steadily rising in prevalence worldwide and significantly impact quality of life in all age groups1. A growing body of literature is revealing that the skin microbiome, the community of bacteria, viruses and fungi present on the skin, plays a significant role in modulating allergic disorders. The microbiome is vital for the development of the immune system and homeostasis. Changes in microbial composition and function, termed dysbiosis, have been linked to alterations in immune responses and to the development of allergic diseases.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: CME Reviews Source Type: research