Partitioning of Chemotherapeutics into Nuclear Condensates —Opening the Door to New Approaches for Drug Development

Klein et  al. (2020) demonstrate for the first time that small-molecule cancer therapeutics are selectively partitioned and concentrated within phase-separated nuclear condensates, providing new insights to drug efficacy and creating the opportunity for enhanced control of therapeutic targeting.

Source: Molecular Cell - August 19, 2020 Category: Cytology Authors: Thomas P. Howard, Charles W.M. Roberts Tags: Spotlight Source Type: research