Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned.

Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned.
Br J Dermatol. 2020 Aug 15;:
Authors: Baeck M, Hoton D, Marot L, Herman A
Abstract
Recently, Colmenero et al (1) demonstrated, by immunohistochemistry, the presence of SARS-CoV-2 in endothelial cells of skin biopsy specimens of chilblains in seven patients. These results raise some questions: The presence of the virus at cutaneous and vascular levels in otherwise asymptomatic patients with negative RT-PCR is unexpected. Vascular damage by direct viral effect is expected to be a sign of severity. It is also surprising that only feet are affected.
PMID: 32798309 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - August 14, 2020 Category: Dermatology Authors: Baeck M, Hoton D, Marot L, Herman A Tags: Br J Dermatol Source Type: research