Epidemiology and outcomes of novel coronavirus 2019 in patients with immune-mediated inflammatory diseases
This article analyzes peer-reviewed research on the epidemiology and outcomes of COVID-19 in those with IMID.
Recent findings
Published literature on approximately 1400 patients was included from rheumatology, gastroenterology, and dermatology. Data suggest that those who are older and have comorbidities have poorer outcomes. This is consistent with the reports from the general population of patients with COVID-19. Adjusted analyses from the largest published studies demonstrate independent effects of systemic glucocorticoids, as well as age and comorbidities with poorer COVID-19 outcomes (SECURE-IBD registry, nā=ā525; COVID-19 Global Rheumatology Alliance registry, nā=ā600); biologic or targeted synthetic disease-modifying antirheumatic drug therapy has not been associated with more severe outcomes. These early results will require validation in population-based studies as more data becomes available.
Summary
Current data suggest that similar to the general population, age, and comorbidities are risk factors for poorer COVID-19 outcomes in patients with IMID. Additional research is needed to quantify outcomes and risk across rheumatic disease types, comorbidities, and immunosuppressive drugs.
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: RHEUMATOLOGICAL ASPECTS OF COVID-19: Edited by Leonard H. Calabrese and Cassandra Calabrese Source Type: research
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