Unlabeled lysophosphatidic acid receptor binding in free solution as determined by a compensated interferometric reader [Methods]

In conclusion, FSA-CIR offers a new increased-throughput approach to assess quantitatively label-free lipid ligand-receptor binding, including nonactivating antagonist binding, under near-native conditions.

Source: The Journal of Lipid Research - July 31, 2020 Category: Lipidology Authors: Ray, M., Nagai, K., Kihara, Y., Kussrow, A., Kammer, M. N., Frantz, A., Bornhop, D. J., Chun, J. Tags: Methods Source Type: research