COVID-19:   More Evidence of Delayed Diabetes Diagnosis in Kids COVID-19:   More Evidence of Delayed Diabetes Diagnosis in Kids

In Germany, the COVID-19 pandemic lockdown resulted in further elevation of the already increasing proportion of children and adolescents with new-onset type 1 diabetes presenting in DKA.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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This study is open label.Numbers to be randomized (sample size)For Group 1, a sample size of about 2000 SARS-CoV-2-exposed subjects such as household members and/or contacts of COVID-19 patients will take part in the study. Assuming around 1.5-2.0 asymptomatic household members and/or contacts for each COVID-19 patient, we expect to identify approximately 1000-1300 COVID-19 index cases to be randomized. An interim analysis on efficacy is planned using standard alpha-spending function.For Group 2, sufficient power for primary objective (negative swab within 14 days of randomization) will be reached given a sample size of 30...
Source: Trials - Category: Research Source Type: clinical trials
In Germany, the COVID-19 pandemic lockdown resulted in further elevation of the already increasing proportion of children and adolescents with new-onset type 1 diabetes presenting in DKA.Medscape Medical News
Source: Medscape Emergency Medicine Headlines - Category: Emergency Medicine Tags: Diabetes & Endocrinology News Source Type: news
Spain has been one of the worst affected countries by the COVID-19 pandemic. A very strict lockdown at home was imposed with a tough restriction of mobility. We aimed to evaluate the impact of this exceptional scenario on glucose profile of patients with T1D prone to hypoglycemia using standalone continuous glucose monitoring.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
The COVID-19 pandemic has forced governments to take exceptional measures to minimize its spread, imposing lockdown policies. The aim of this study was to evaluate the impact of lockdown on type 1 diabetes (T1D) glycemic control.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
This study uses diabetes registry data to compare the frequency of diabetic ketoacidosis (DKA) in children and adolescents at time of type 1 diabetes diagnosis in Germany during the first 2 months of the coronavirus disease 2019 (COVID-19) pandemic vs the same time period in 2018 and 2019.
Source: JAMA - Journal of the American Medical Association - Category: General Medicine Source Type: research
ConclusionCOVID-19 with T1D presents special challenges. While the available evidence does shed some light, we need more evidence to deal with this difficult duo.
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research
Authors: Dworakowska D, Grossman AB Abstract COVID-19, which is caused by the single-stranded RNA severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has introduced significant therapeutic dilemmas in several areas. One of these is concern regarding the use of renin-angiotensin system (RAS) inhibitors. Dysfunction of the RAS has been observed in COVID-19 patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type-1 receptor blockers (ARBs), are associated with improved or worse clinical outcomes, remains unclear. RAS inhibitors are currently widel...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
JDRF, the world's leading type 1 diabetes charity, is partnering with Diabetes UK to find out how the coronavirus pandemic is affecting people with type 1 diabetes.
Source: University of Bristol news - Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Translational Health Sciences; Press Release Source Type: news
At the dawn of 2020, central China faced the outbreak of a highly transmittable, novel strain of the coronavirus, causing severe Illness that was subsequently named SARS-CoV-2 [1]. The coronavirus disease 19 (COVID-19) is characterized by severe acute respiratory syndrome and has a high mortality rate especially among the elderly and people with serious underlying medical conditions irrespectively of age [2]. By the 11th of March and as more than 110 countries have reported numerous cases of COVID-19, WHO declared this outbreak as a pandemic [3].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
Management of Type 1 Diabetes (T1D) poses numerous challenges, especially for young children and their families. Parental care positively influencesthe outcomesofchildren with T1D, while there are often criticisms in school environment. The COVID-19 pandemic has forced children and parents to spend many hours at home and diabetes care has returned mainly in the hands of parents.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
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