Taking hormone replacement therapy to cope with the menopause 'cuts risk of common infections'
Researchers from the University of Texas, in Dallas, found that women who take hormone replacement therapy are less at risk of contracting urinary tract infections
ConclusionIn peri-menopausal and menopausal women, the risks and benefits of chronic NF therapy should be weighed by the clinician and patient prior to prescribing long term NF. Patients must be educated about the potential NF toxicities and clinically monitored for signs and symptoms of potential adverse events while on chronic NF therapy.
MONDAY, July 20, 2020 -- Hormone replacement therapy (HRT) might be able to break the cycle of recurring urinary tract infections in some women, a new study reports. Women taking HRT for symptoms of menopause tend to have a greater variety of...
We present a large-scale study exploring factors defining urinary microbiome composition in community-dwelling older adult women without clinically active infection. Using 1,600 twins, we estimate the contribution of genetic and environmental factors to microbiome variation. The urinary microbiome is distinct from nearby sites and unrelated to stool microbiome with more Actinobacteria, Fusobacteria and Proteobacteria, but fewer Bacteroidetes, Firmicutes and Verrumicrobia. A quarter of variants had heritability estimates greater than 10% with most heritable microbes having potential clinical relevance, including Escherichia...
This review article explores the occurrence of urinary tract infection in women – in pregnancy, in gynaecology, after menopause as well as those that are acquired in hospitals. It discusses the pathophysiology of these infections and the evidence that is currently present for different management modalities. It also discusses in-depth, the various causes and treatment modalit ies for recurrent urinary tract infections including the burden that it can bear on women and society.
Date: August 10, 2020 Issue #: 1604Summary: The primary symptoms of menopause are genitourinary (genitourinary syndrome of menopause; GSM) and vasomotor (VMS). Vulvovaginal atrophy can cause vaginal burning, irritation and dryness, dyspareunia, and dysuria, and increase the risk of urinary tract infections. Vasomotor symptoms ( " hot flashes " ) cause daytime discomfort and night sweats that may disrupt sleep. Hormone therapy is the most effective treatment for both genitourinary and vasomotor symptoms.
To review the available data related to the prevention of recurrent urinary tract infection (rUTI) in postmenopausal women with vaginal estrogen preparations and provide the urologic community with the confidence to identify and treat genitourinary syndrome of menopause (GSM).
Conclusion: No clear association exists between polypropylene MUS placement and subsequent urethral diverticulum formation. Factors that diminish polypropylene mesh biocompatibility include elevated BMI, menopause, recurrent UTIs, prior pelvic surgeries, and preexisting medical conditions. Symptoms associated with urethral diverticula should prompt a complete urologic workup prior to MUS placement. PMID: 32462011 [PubMed - in process]
ConclusionAlthough there are many causes of recurrent urinary tract infections, this study showed that vaginal pH imbalance and labia minora anatomy in the lower third prominence based on the Banwell classification (type 3) were among the most important causes. Thus, we think that the vaginal anatomy should be evaluated in recurrent UTI patients.
Conditions: Urinary Tract Infections; Menopause Intervention: Sponsor: Hadassah Medical Organization Not yet recruiting
AbstractPurpose of ReviewThe purpose of this review article is to summarize the recent literature regarding the effect of hormone replacement therapy on pelvic floor disorders and its role as a preventative or treatment option.Recent FindingsThe recent evidence describing the effect of hormone replacement therapy on pelvic floor disorders is mainly limited to cohort studies, systematic reviews, and secondary analysis of randomized controlled trials such as the Women ’s Health Initiative and Nurses’ Health Study. There are few quality randomized controlled trials, especially within the last 5 years on this ...