Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

AbstractTwo new tri-ferulates of sucrose, firmosides A and B (1 and2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts ofSilene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization –mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1,2) and11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents.Graphic Abstract
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research