Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression

The role of histone modifications is poorly characterized in breast cancer, especially within the major subtypes. While epigenetic modifications may enhance the adaptability of a cell to both therapy and the s...

Source: BMC Medical Genomics - July 3, 2020 Category: Genetics & Stem Cells Authors: Damien Kaukonen, Riina Kaukonen, L élia Polit, Bryan T. Hennessy, Riikka Lund and Stephen F. Madden Tags: Research article Source Type: research