IL-33/13 Axis and IL-4/31 Axis Play Distinct Roles in Inflammatory Process and Itch in Psoriasis and Atopic Dermatitis.

Conclusion: IL-31 is the key mediator for pruritus in both AD and Ps patients. IL-4/31 axis and IL-33/13 axis play distinct roles in the pathogenesis of Atopic dermatitis and Psoriasis. Interleukin serum levels were not correlated with itch and disease severity in both conditions. PMID: 32606880 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/32606880?dopt=Abstract

Source: Clinical, Cosmetic and Investigational Dermatology - July 2, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research