QuantiFERON TB-gold conversion is not uncommon in psoriasis patients under anti-TNF- α.

QuantiFERON TB-gold conversion is not uncommon in psoriasis patients under anti-TNF-α. Br J Dermatol. 2020 Jun 12;: Authors: Megna M, Ruggiero A, Ferrillo M, Fabbrocini G Abstract Tuberculosis (TB) screening and eventual TB infection prophylaxis in case of screening positivity for latent TB infection (LTBI) are mandatory before starting a biologic treatment for psoriasis.1 Indeed, opportunistic infections reactivation, especially LTBI, is one the main risk during biologic therapy, in particular with tumour necrosis factor (TNF)-α inhibitors. It is already known that TNFα plays a major role in the initial and long-term control of TB. PMID: 32531802 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research