Influenza a virus antagonizes type I and type II interferon responses via SOCS1-dependent ubiquitination and degradation of JAK1

Although influenza A virus (IAV) employs diverse strategies to evade IFN responses by inhibiting the synthesis of IFN, how IAV regulates signaling downstream of IFN is incompletely understood.

Source: Virology Journal - June 12, 2020 Category: Virology Authors: Yinping Du, Fan Yang, Qiuxia Wang, Nuo Xu, Yizhang Xie, Sujuan Chen, Tao Qin and Daxin Peng Tags: Research Source Type: research