From Vertigo to Tinnitus, Ear Ailments Are New Focus for Drugs

In search of an alternative to hearing aids or implants, some report success in early trials for drugs to improve hearing or silence tinnitus.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Clinical Trials Ears and Hearing Drugs (Pharmaceuticals) Roche Holding AG Tinnitus Avalon Ventures Limited GlaxoSmithKline PLC Pfizer Inc Novartis AG Source Type: news

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We report a dramatic presentation of Sporothrix brasiliensis infection, with destruction of the nasal septum, soft palate, and uvula of an HIV-infected woman. She was successfully treated with amphotericin B deoxycholate followed by itraconazole. Sporotrichosis remains a neglected opportunistic infection in patients with AIDS and awareness of this potentially fatal infection is of utmost importance.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research
Publication date: January 2019Source: International Journal of Industrial Ergonomics, Volume 69Author(s): Alex M. Noonan, Michael Solomon, Diane E. Gregory, Jamie F. Burr, Stephen H.M. BrownAbstractDue to the increased popularity of standing-based occupational work stations there is a growing need to understand the impact of ergonomic aids such as standing mats. In particular, while standing mats have been studied in relation to musculoskeletal discomfort and pain, there have been no studies exploring the effects of their use on metabolism and caloric expenditure. The purpose of this study was to examine the metabolic, bio...
Source: International Journal of Industrial Ergonomics - Category: Occupational Health Source Type: research
Conditions:   Tuberculosis;   HIV/AIDS Intervention:   Other: Combination of TB/HIV prevention activities Sponsors:   London School of Hygiene and Tropical Medicine;   Zambart;   Health Systems Trust, South Africa;   International Union Against Tuberculosis and Lung Diseases;   KNCV Tuberculosis Foundation;   Imperial College London;   University of Sheffield;   QIAGEN GmbH, Germany;   Delft Imaging Systems BV (Delft), Netherlands Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
November 14, 2018Communities in two regions can now transport urgent cases from health huts to larger facilities —and more are following suit.en fran çaisImagine you are a mother in a remote village and your one-year-old daughter is diagnosed with severe malaria. If left untreated, it will kill her.  Imagine that the nurse at the nearest health post tells you he doesn ’t have the medicine necessary to help your daughter.Imagine there is no ambulance, no safety net, and no way for you to get her the urgent help she needs, leaving you with one unimaginable option —watching her die. In Seneg...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
AbstractThe aim of this study was to determine the frequency, clinical and radiological features, and efficacy of clinical evaluation and perfusion-weighted imaging (PWI) for the prediction of final stroke in patients with DWI/MRI-negative posterior circulation stroke (PCS) presenting acute dizziness/vertigo. From our comprehensive prospective stroke registry of acute ischemic stroke during a 7-year period, we identified 1846 consecutive patients with PCS, 850 of whom presented with acute dizziness/vertigo. Of these 850 patients, initial DWI-MRI was negative in 35 (4.1%). In these 35 patients, dizziness/vertigo was acute p...
Source: Journal of Neurology - Category: Neurology Source Type: research
ConclusionsCurrent therapeutic strategies have proven that the goal of the traditional oriental medicine principle of increasing bodily fluids is a relevant approach for reducing the development of hearing loss by improving microcirculation in the blood-labyrinth barrier and increasing cochlear blood flow. The potential benefits of TOM agents expand to a multi-target approach on different auditory structures of the inner ear related to increased cochlear blood flow, antioxidant, anti-inflammatory, anti-apoptotic and neuroprotective activities. TOM is proposed as an important source of drug discovery and well-controlled, do...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Dural amyloidoma is an unusual presentation of central nervous system amyloidosis. A 49-year-old woman presented with 1-month history of repeated episodes of vertigo. Precontrast MRI showed dural thickening over right frontal convexity with signal intensity similar to white matter. Postcontrast T1-weighted images showed remarkable enhancement of the lesion. Dural amyloidoma was confirmed by partial resection of the lesion. The patient underwent no further treatment. A follow-up FDG PET/CT showed increased FDG uptake of the residual dural amyloidoma. This case indicates dural amyloidoma should be included in the differentia...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
[Bhekisisa] A company touted a fake "potential HIV cure". Now, it admits its "trial" wasn't registered&it can't explain the poor treatment Ugandan patients got
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Today, 1989 may be most associated with Taylor Swift: It is the album that won her a second Grammy for Album of the Year. Not only that, it happens to be the year Swift was born--such a long, long time ago! People under 35 have no personal memory of 1980s pop culture, which is ironic since Swift's album in part pays homage to it. In the real 1989 (no offense to Swift and the 10 co-producers who made the album), all sorts of revolutions took place: Mr. Gorbachev tore down that pesky wall, for example. America's greatest antagonist, the Soviet Union, collapsed in 1989. Brazil conducted its first democrat...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
"I wonder how you're feeling There's ringing in my ears And no one to relate to 'cept the sea..." -- Peter Frampton There are few afflictions as constant and annoying as tinnitus, which Wikipedia defines as: "The hearing of sound when no external sound is present. While often described as a ringing, it may also sound like a clicking, hiss or roaring. Most of the time, it comes on gradually. In some people, the sound causes depression, anxiety or interferes with concentration." It is a surprisingly common condition with chronic tinnitus affecting 5 to 10 percent of the U.S. adult population, with about 0...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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