Impact of chorioamnionitis on maternal and fetal levels of proinflammatory S100A12

Conclusion:S100A12 did neither identify mothers with HCA nor very preterm infants exposed to HCA. It is currently unknown if S100A12 may identify neonates with FIRS.What is known:• Histologic chorioamnionitis (HCA) may lead to the fetal inflammatory response syndrome (FIRS).• S100A12 represents an early, sensitive, and specific diagnostic marker of inflammatory processes.What is new:• S100A12 did neither identify mothers with HCA nor very preterm infants exposed to HCA.• It is currently still unclear if S100A12 has a potential in identifying preterm infants with FIRS.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research