Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia

Hypoxia inducible factor-1 (HIF-1) is considered as the most activated transcriptional factor in response to low oxygen level or hypoxia. HIF-1 binds the hypoxia response element (HRE) sequence in the promoter...

Source: Biological Research - June 5, 2020 Category: Biomedical Science Authors: Fatemeh Sadeghi, Gholam Ali Kardar, Mohammad Reza Bolouri, Farzad Nasri, Maryam Sadri and Reza Falak Tags: Research article Source Type: research