Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity

Chem. Commun., 2015, Accepted ManuscriptDOI: 10.1039/C4CC09859E, CommunicationHui Gao, Hiroyasu Takemoto, Qixian Chen, Mitsuru Naito, Hirokuni Ucida, Xueying Liu, Kanjiro Miyata, Kazunori KataokaEffects of repeated number (RN) of aminoethylene (AE) units in polyaspartamide side chains were investigated for polyion complex (PIC)-based siRNA delivery. Reduction of apparent RN from 3 to 2 by...The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - January 9, 2015 Category: Chemistry Authors: Hui Gao Source Type: research