Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter

A long-term opioid use has been associated with hypermethylation of the opioid receptor mu 1 (OPRM1) promoter. Very little is currently known about the early epigenetic response to therapeutic opioids. Here, we e...

Source: Clinical Epigenetics - June 3, 2020 Category: Research Authors: Jose Vladimir Sandoval-Sierra, Francisco I. Salgado Garc ía, Jeffrey H. Brooks, Karen J. Derefinko and Khyobeni Mozhui Tags: Research Source Type: research