2-18FFDG PET/CT radiomics in lung cancer: an overview of the technical aspect and its emerging role in management of the disease
Publication date: Available online 1 June 2020Source: MethodsAuthor(s): Reyhaneh Manafi-Farid, Najme Karamzade-Ziarati, Reza Vali, Felix M. Mottaghy, Mohsen Beheshti
New proposals to start screening at age 50 rather than 55, and after 20 rather than 30 pack-years of smoking, could benefit Black persons and women, say experts.Medscape Medical News
Authors: Guo S, Zhang J, Zhao YY, Zhou LY, Xie Y, Wu XY, Bian X, Yu XY Abstract OBJECTIVE: To investigate the expressions of miR-151a-5p and miR-23b in lung cancer tissues and their effects on the biological functions of lung cancer A549 cells. PATIENTS AND METHODS: Samples of lung cancer tissue (55 cases) and pericarcinomatous tissue (55 cases) were collected in thoracic surgery in our hospital from May 2017 to November 2018. The expression levels of miR-151a-5p and miR-23b in lung cancer tissues and pericarcinomatous tissues were detected by RT-PCR. Lung cancer cells A549 were transfected. Before transfection...
CONCLUSIONS: These data suggested that circFOXP1 promoted cell proliferation and repressed cell apoptosis in LUAD by regulating miR-185-5p/WNT1 signaling pathway. It provides a novel potential therapeutic agent for the treatment of LUAD. PMID: 32633368 [PubMed - in process]
Authors: Huang L Abstract OBJECTIVE: To investigate the expression and clinical significance of costimulatory molecule B7-H3 and microRNA-145 (miR-145) in lung cancer patients with malignant pleural effusion. PATIENTS AND METHODS: A total of 100 cases of patients with lung cancer who admitted to our hospital for treatment from March 2017 to September 2018 were selected. Forty-nine cases of patients diagnosed with malignant pleural effusion were included in the study group, and 51 cases with benign pleural effusion in the control group. The content of B7-H3 in pleural effusion of the two groups was detected by e...
CONCLUSIONS: LINC00460 is overexpressed in NSCLC tissues and can promote the growth of NSCLC cells by targeting miR-539. PMID: 32633366 [PubMed - in process]
Publication date: Available online 9 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Shane P. Smith, Adam J. Bograd, Gal Levy, Shu-Ching Chang, Alex S. Farivar, Ralph W. Aye, Brian E. Louie, Eric Vallières
(Translational Research Institute) Scientists have developed a new cancer vaccine with the potential to activate the body's immune system to fight a range of cancers, including leukaemia, breast cancer, lung cancer and pancreatic cancers.
(Institute of Cancer Research) Lung cancer in non-smokers is a biologically distinct disease from that in smokers, according to a new study. Researchers also found that non-smokers have signs of genetic damage from environmental carcinogens and that some cancers look molecularly like more advanced disease - with characteristics that could be targeted with tailored treatments.
CONCLUSIONS: Coverage of ctDNA-based panel testing for cancer indications increased from 2015 to 2019. The trend in private payer and Medicare coverage is an increasing number of coverage policies, number of positive policies, and scope of coverage. We found that Medicare coverage policies are evolving to pan-cancer uses, signifying a significant shift in coverage frameworks. Given that genomic medicine is rapidly changing, payers and policymakers (eg, guideline developers) will need to continue to evolve policies to keep pace with emerging science and standards in clinical care. PMID: 32634780 [PubMed - as supplied by publisher]
The objective of this study was to examine receipt of anticancer therapy, death, readmission, and hospice use among patients with cancer who discharge to an SNF compared with those who are functionally able to discharge to home or home with home healthcare in the 6 months after an acute care hospitalization. METHODS: A population-based cohort study was conducted using the SEER-Medicare database of patients with stage II-IV colorectal, pancreatic, bladder, or lung cancer who had an acute care hospitalization between 2010 and 2013. A total of 58,770 cases were identified and patient groups of interest were compared descr...