It Takes Two to Tango

This study, however, provides a framework for understanding vitiligo: Skin resident CD8 T cells recognize and kill melanocytes through NKG2D signaling. This event results in the increased production and release of cyto/chemokines and the development of long-lasting CD8 T cells, which in turn causes the recruitment of new T cells, thus perpetuating and disseminating the disease.

Source: Journal of Investigative Dermatology - May 20, 2020 Category: Dermatology Authors: Jos é A. Guevara-Patiño, Lourdes Plaza-Rojas Tags: Commentary Source Type: research