Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial

Postoperative delirium, an acute confusional state arising after surgery, is caused by an underlying physiological disturbance and characterized by sleep/wake cycle disturbances. (1) It is a serious public health problem that disproportionately affects older people. (2) Delirium is associated with many negative outcomes including: increased mortality, longer hospital stays, increased institutionalization after acute care hospitalization, worse cognitive and physical outcomes (both short- and long-term), and significant distress for patients and their families.

Source: The American Journal of Geriatric Psychiatry - May 15, 2020 Category: Geriatrics Authors: Esther S Oh, Jeannie-Marie Leoutsakos, Paul B Rosenberg, Alexandra Pletnikova, Harpal S Khanuja, Robert S. Sterling, Julius K Oni, Frederick E Sieber, Neal S Fedarko, Narjes Akhlaghi, Karin J Neufeld Tags: Regular Research Article Source Type: research