Precision toxicity correlates of tumor spatial proximity to organs at risk in cancer patients receiving intensity-modulated radiotherapy

Radiation-associated dysphagia (RAD) is one of the severe sequelae of treatment in head and neck (HNC) cancer patients undergoing radiation therapy (RT), with chronic toxicity arising even after acute symptoms have ceased [1]. Chronic RAD is even more relevant in the era of Human Papillomavirus associated (HPV) HNC, where the majority of patients have curable disease with prolonged survival, and thereby endure later toxicities which are otherwise not encountered in patients with aggressive HPV negative disease and relatively shorter survival duration.

Source: Radiotherapy and Oncology - May 14, 2020 Category: Radiology Authors: Andrew Wentzel, Peter Hanula, Lisanne V. van Dijk, Baher Elgohari, Abdallah S. R. Mohamed, Carlos E. Cardenas, Clifton D. Fuller, David M. Vock, Guadalupe Canahuate, G. Elisabeta Marai Tags: Original Article Source Type: research