Feasibility study of a surface-coated lung model to quantify active agent deposition for preclinical studies

The model represents an integral system for continuous, spatial detection of aerosol deposition and allows the analysis of bacterial behaviour and the toxicity of the active agent. Thus, the deposition of antimicrobial aerosols on the bronchial surfaces is characterized in preliminary tests without any animal experiments.

Source: Clinical Biomechanics - May 9, 2020 Category: Orthopaedics Authors: Philipp D örner, Philipp M. Müller, Jana Reiter, Martin C. Gruhlke, Alan J. Slusarenko, Wolfgang Schröder, Michael Klaas Source Type: research