Prestin at Year 14: Progress and Prospect.

This article reviews recent advances of the structural and functional properties of prestin with focus on the areas that are critical but still controversial in understanding the molecular mechanism of how prestin works: The structural domains for voltage sensing and interaction with anions and for conformational change. Future research directions and potential application of prestin are also discussed.
PMID: 24361298 [PubMed - as supplied by publisher]

Source: Hearing Research - December 17, 2013 Category: Audiology Authors: He DZ, Lovas S, Ai Y, Li Y, Beisel KW Tags: Hear Res Source Type: research