Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

Adapter chimeric antigen receptor (CAR) approaches have emerged has promising strategies to increase clinical safety of CAR T-cell therapy. In the UniCAR system, the safety switch is controlled via a target mo...

Source: Journal of Experimental and Clinical Cancer Research - May 5, 2020 Category: Cancer & Oncology Authors: Liliana R. Loureiro, Anja Feldmann, Ralf Bergmann, Stefanie Koristka, Nicole Berndt, Domokos M áthé, Nikolett Hegedüs, Krisztián Szigeti, Paula A. Videira, Michael Bachmann and Claudia Arndt Tags: Research Source Type: research