Skin microbiome in cutaneous T cell lymphoma by 16S and whole genome shotgun sequencing

The development of DNA sequencing methods have widened our conceptions of cutaneous microbial communities (Byrd et al., 2018, Eyerich et al., 2018, Fyhrqvist et al., 2016). Recently, we investigated the cutaneous microbiome in parapsoriasis, but did not find significant differences between healthy skin and diseased skin with the 16S method (Salava et al., 2017). In vitro studies have demonstrated associations between staphylococcal enterotoxins and cutaneous T cell lymphoma (CTCL) (Krejsgaard et al., 2014, Willerslev-Olsen et al., 2013, Bl ümel et al., 2019).

Source: Journal of Investigative Dermatology - April 26, 2020 Category: Dermatology Authors: Alexander Salava, Paulina Deptula, Annina Lyyski, Pia Laine, Lars Paulin, Liisa V äkevä, Annamari Ranki, Petri Auvinen, Antti Lauerma Tags: Letters to the Editor Source Type: research