The Single Administration of a Chromophore Alleviates Neural Defects in Diabetic Retinopathy

Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of blindness among the working-age population. Diabetic patients often experience functional deficits in dark adaptation, contrast sensitivity and color perception before any microvascular pathologies on the fundus become detectable. Previously, we found that the regeneration of 11-cis-retinal and visual pigment is impaired in a type 1 diabetes animal model, which negatively affects the visual function at the early stage of DR.
Source: American Journal of Pathology - Category: Pathology Authors: Source Type: research