DDX5 potentiates HIV-1 transcription as a co-factor of Tat

HIV-1 does not encode a helicase and hijacks those of the cell for efficient replication. We and others previously showed that the DEAD box helicase, DDX5, is an essential HIV dependency factor. DDX5 was recen...

Source: Retrovirology - March 30, 2020 Category: Virology Authors: Nyaradzai Sithole, Claire A. Williams, Truus E. M. Abbink and Andrew M. L. Lever Tags: Research Source Type: research