How Mutations Affect Structural Characteristics and Substrate Binding of CYP21A2? An Investigation by Molecular Dynamics Simulations

Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP00763C, PaperBai-Hui Lin, Hong-Xing Zhang, Qing-Chuan Zheng Congenital adrenal hyperplasia (CAH) is one of the most frequent inborn errors of metabolism, inherited in an autosomal recessive trait. Above 95% cases of CAH are caused by mutations in... The content of this RSS Feed (c) The Royal Society of Chemistry
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