Local application of enamel matrix derivative prevents acute systemic inflammation after periodontal regenerative surgery: A randomized controlled clinical trial.
CONCLUSIONS: The adjunctive application of EMD during surgical treatment resulted in a minor increase in serum CRP 24-hr after surgery. These findings suggest a possible systemic anti-inflammatory effect of EMD. Within its limitations, this pilot trial confirmed better clinical periodontal outcomes in the EMD group. NCT03590093.
PMID: 32163634 [PubMed - as supplied by publisher]
Source: Journal of Clinical Periodontology - Category: Dentistry Authors: Graziani F, Peric M, Marhl U, Petrini M, Bettini L, Tonetti M, Gennai S Tags: J Clin Periodontol Source Type: research