Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model

Dopamine-replacement utilizing L-DOPA is still the mainstay treatment for Parkinson ’s disease (PD), but often leads to development of L-DOPA-induced dyskinesia (LID), which can be as debilitating as the motor ...

Source: BMC Research Notes - March 12, 2020 Category: Research Authors: Mitchell J. Bartlett, Lisa Y. So, Lajos Szab ò, David P. Skinner, Kate L. Parent, Michael L. Heien, Todd W. Vanderah, Robin Polt, Scott J. Sherman and Torsten Falk Tags: Research note Source Type: research