Very-high-risk localized prostate cancer: definition and outcomes

Very-high-risk localized prostate cancer: definition and outcomes Prostate Cancer and Prostatic Diseases advance online publication, November 5 2013. doi:10.1038/pcan.2013.46 Authors: D Sundi, V M Wang, P M Pierorazio, M Han, T J Bivalacqua, M W Ball, E S Antonarakis, A W Partin, E M Schaeffer &A E Ross
Source: Prostate Cancer and Prostatic Diseases - Category: Urology & Nephrology Authors: Tags: high-risk prostate cancer survival metastasis Source Type: research

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Objectives: We sought to evaluate sociodemographic disparities in insurance coverage among nonelderly adults with a common cancer after Affordable Care Act (ACA) implementation. Patients and Methods: In total, 109,182 patients aged 18 to 64 years diagnosed with a common cancer (lung, breast, or prostate cancer) were identified from 2010 to 2014. Multivariable logistic regressions analyzed associations between ACA implementation and uninsured rates on the basis of state approach to Medicaid expansion, stratified by race (black, white), and income (stratified at 138% Federal Poverty Line). Results: Uninsured rates de...
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Health Policy Source Type: research
PMID: 32092344 [PubMed - as supplied by publisher]
Source: Ann Oncol - Category: Cancer & Oncology Authors: Tags: Int J Radiat Oncol Biol Phys Source Type: research
Authors: Nieder C, Dalhaug A, Haukland E Abstract Aim: The aim of this study was to evaluate the feasibility and efficacy, in terms of overall survival, of sequential systemic therapy in patients with metastatic castration-resistant prostate cancer (MCRPC) who lived in Nordland County, Norway, a large region with a challenging geography, yet only one department of oncology located in the main city, Bodø.Patients and methods: Overall 77 patients who had received at least 2 lines of treatment were included in this retrospective study.Results: Management included docetaxel in 69 patients (90%), often prescribed...
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
Publication date: Available online 24 February 2020Source: Journal of the American College of RadiologyAuthor(s): Julianna M. Czum
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
CONCLUSION: NSD2 expression is abnormal in almost 80% of patients with advanced PCa. Expression levels of this epigenetic regulator are easily detected by immunohistochemistry while this biomarker exhibited prognostic value for PCa progression and death in univariable analysis. Further studies on NSD2 involvement in PCa proliferation, progression, metastasis and resistance mechanisms are needed. PMID: 32091270 [PubMed - as supplied by publisher]
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research
Conditions:   Establish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification;   Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique;   Establish the Efficacy Between the Four Schemes in Term s of the Patient's Subjective Perception Regarding Pain and Quality of Life;   Establish the Association of the Tumor Biomarker in the Early Detection and Aggressiveness of Tumors;   Establish the Possible Interaction Between Biomarkers and Resonance in Different Prostate Biopsy Models to Define...
Source: - Category: Research Source Type: clinical trials
Condition:   Prostate Carcinoma Interventions:   Procedure: Biospecimen Collection;   Procedure: Computed Tomography;   Drug: Gallium Ga 68-labeled PSMA-11;   Dietary Supplement: Monosodium Glutamate;   Procedure: Positron Emission Tomography Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI) Recruiting
Source: - Category: Research Source Type: clinical trials
AbstractObjectiveTo assess the use of the cell cycle progression (CCP) score versus actual risk stratification practice in making treatment decisions for prostate cancer patients with locally adverse pathology after radical prostatectomy (RP).Patients and methodsMen with adverse pathologic features, pT3 or positive surgical margins who underwent RP in 2010 –2014 at Renji hospital were retrospectively analyzed. The primary outcome was biochemical recurrence (BCR) after RP. RNA was quantified from paraffin-embedded RP specimens. The CCP score was calculated as average expression of 31 CCP genes, normalized to 15 housek...
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Jeremy Clarke already had the cancer. But a doctor told his 46-year-old brother he didn't need to be checked. Now they're both fighting for survival.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionConsumption of canned and cooked tomatoes may reduce the risk of prostate cancer. These products contain more available lycopene. However, an observational study cannot exclude confounding by some unidentified, prostate cancer preventive factor.Clinical Trial Registry: Identifier: NCT03615599
Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
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