Long-term impact of acute restraint stress on heroin self-administration, reinstatement, and stress reactivity

ConclusionsAcute restraint stress results in anxiety-like behaviors and a stress-associated cue is sufficient to reinstate extinguished heroin seeking. This project has the potential to elucidate the complex relationship between stress/anxiety disorders, including some PTSD-like characteristics, and the onset, maintenance, and relapse to heroin seeking.
Source: Psychopharmacology - Category: Psychiatry Source Type: research