A Comprehensive Review of Treatment Options for Recalcitrant Nongenital Cutaneous Warts.

Conclusions: Many upcoming treatment modalities, especially immunotherapy, are promising. However, more comparative studies are required to verify the efficacy and safety profile. PMID: 32116076 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research

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Background: New treatment options for warts include intralesional wart injection with agents such as vitamin D, measles, mumps, and rubella (MMR) vaccine antigen, Bacillus Calmette-Guerin (BCG) antigen, and candida antigen but there have been limited studies to compare their efficacies. Background: New treatment options for warts include intralesional wart injection with agents such as vitamin D, measles, mumps, and rubella (MMR) vaccine antigen, Bacillus Calmette-Guerin (BCG) antigen, and candida antigen but there have been limited studies to compare their efficacies. Objective: The purpose of this systematic review is to...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
Authors: Vania R, Pranata R, Tan ST Abstract Introduction: Warts can be difficult to treat and progressing to chronic and resistant disease. Several studies have reported the successful application of mumps-measles-rubella (MMR) vaccine resulting in clearance of warts via immunomodulation and induction of immune system.Methods: We performed a comprehensive search on the role of intralesional MMR in warts from several electronic databases. Complete response is defined as complete clearance of warts lesion.Results: There were a total of 425 subjects from five studies. Intralesional injection of MMR was associated wit...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
New wart treatment involves injecting the measles, mumps and rubella (MMR) vaccine into warts which could banish the skin growths for good. The patients would receive four doses of it.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Because of rich sensory innervation, any injection  into the digits is a singularly unpleasant experience for patients (eg, injection of lidocaine for local anaesthesia; the measles, mumps, and rubella (MMR) vaccine1; or purified protein derivative for warts on the digits).
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Tags: JAAD Online: Therapeutic pearl Source Type: research
In this study it was assumed that there was no immunity following resolution of natural infection. The modeling demonstrated that a vaccine of moderate efficacy could have a significant impact on the prevalence of gonorrhea if strategically implemented (23). While encouraging it does, of course, depend on the availability of a vaccine. From Ecological Data to Evidence The epidemiological evidence from Cuba, Brazil, and New Zealand demonstrates that N. meningitidis OMV vaccines are possibly able to provide some broader protection against meningococcal disease (17, 24), particularly in older children and adults (25). These...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We describe the use of a single intralesional treatment with the measles, mumps, and rubella (MMR) vaccine to successfully eliminate both local and distant recalcitrant warts as well as the proposed mechanism of this method. There are no other known reports of complete wart regression at distant untreated sites after a single intralesional MMR treatment.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
We describe the use of a single intralesional treatment with the measles, mumps, and rubella (MMR) vaccine to successfully eliminate both local and distant recalcitrant warts as well as the proposed mechanism of this method. There are no other known reports of complete wart regression at distant untreated sites after a single intralesional MMR treatment. PMID: 30677806 [PubMed - in process]
Source: Dermatol Online J - Category: Dermatology Authors: Tags: Dermatol Online J Source Type: research
We report the two cases of genital warts, who had an excellent response with intralesional MMR vaccine.
Source: Indian Journal of Sexually Transmitted Diseases - Category: Infectious Diseases Authors: Source Type: research
Introduction: Viral warts are common skin lesions caused by human papilloma virus (HPV) infection. The superficial epidermis is infected with HPV, causing keratinocyte proliferation and hyperkeratosis. Although benign, they may be tender and cosmetically bothersome. In some cases, warts are recalcitrant to conventional therapies including topical agents, cryotherapy, electrosurgery, and laser ablation. The use of intralesional injections of measles-mumps-rubella vaccine represents a novel immunologic modality of treatment for recalcitrant warts and will prove particularly useful for patients who are less suitable for surge...
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Date: May 7, 2018 Issue #:  1546Summary:  The US Advisory Committee on Immunization Practices (ACIP) recommends routine use of the following vaccines in adults residing in the US: influenza, tetanus/diphtheria alone (Td) and in combination with acellular pertussis (Tdap), measles/mumps/rubella (MMR), varicella (VAR), herpes zoster (RZV; ZVL), human papillomavirus (HPV), and pneumococcal conjugate (PCV13) and polysaccharide (PPSV23) vaccines. For adults with certain medical conditions or occupational, behavioral, or other risk factors, hepatitis A (HepA), hepatitis B (HepB), meningococcal (MenAC...
Source: The Medical Letter - Category: Drugs & Pharmacology Authors: Tags: ActHIB Avaxim Bexsero Boostrix Cervarix diphtheria Engerix-B Gardasil Gardasil9 Genital warts Haemophilus infuenzae Havrix hepatitis a hepatitis b Heplisav-B Hiberix HPV vaccine Influenza vaccine measles Menactra Me Source Type: research
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