25: Mechanisms underlying nocturia in women with bladder pain syndrome/interstitial cystitis

Little is known about mechanisms underlying nocturia in women with bladder pain syndrome/interstitial cystitis (BPS/IC). The thalamus plays a primary role in the organization of the sleep-wake cycle. Our hypothesis was that nocturia is associated with activation of the thalamus in women with BPS/IC as compared to controls.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Non-Oral Poster Source Type: research

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ConclusionsThe biopsychosocial information provided by our patients will better inform the health care professional on how to develop personalized treatment strategies and also individualized patient directed outcomes independent of bladder pain and urination symptoms.
Source: Urology Practice - Category: Urology & Nephrology Source Type: research
AbstractPurpose of ReviewNon-standard shift work schedules negatively impact the overall health of shift workers, and several studies have shown that shift work, specifically, is detrimental to urogenital health. The aims of this study are to systematically review the literature and determine the effect of shift work on the outcomes of hypogonadism, male infertility, lower urinary tract symptoms, and urogenital cancers.Recent FindingsRecent evidence supports associations between non-standard shift work and an increase in the frequency of prostate cancer and the severity of erectile dysfunction, lower urinary tract symptoms...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
Conclusions: Anti-DFS70 antibodies may represent a useful biomarker for differentiating between FM and other autoimmune diseases. The levels of anti-DFS70 antibodies were also significantly higher among patients with arthralgia and sleep disturbances. Further investigations are necessary to evaluate the relationships between anti-DFS70 antibodies and other cytokines as a predictive marker for pain. PMID: 29166758 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research
Authors: Clauw DJ, Hassett AL Abstract The mechanisms underlying chronic pain states, including osteoarthritis, differ from those underlying acute pain. In chronic pain states, central nervous system (CNS) factors often play a particularly prominent role. In many individuals with chronic pain, pain can occur with minimal or no evidence of ongoing nociceptive input. Medical subspecialties have applied a wide-range of labels to these pain conditions including fibromyalgia, irritable bowel syndrome and interstitial cystitis to name just a few. These same CNS processes can augment or magnify pain when there is ongoing ...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Conclusions The biopsychosocial information provided by our patients will better inform the health care professional on how to both develop personalized management strategies but also individualized patient directed outcomes, independent of bladder pain and urination symptoms.
Source: Urology Practice - Category: Urology & Nephrology Source Type: research
Abstract ObjectiveTo compare fibromyalgia (FM) characteristics among patients identified in a community‐based chronic pain cohort based on traditional International Classification of Diagnoses Ninth Revision, ICD‐9 diagnostic coding, with that of patients identified using a novel predictive model. MethodsThis retrospective study used data collected from July 1999 to February 17, 2015 in multiple chronic pain clinics in the United States. Patients were assigned to the FM case group based on specific inclusion criteria using ICD‐9 codes or, separately, from results of a novel FM predictive model that was developed usin...
Source: Pain Practice - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
Rationale: A variety of therapeutic modalities are available for the treatment of interstitial cystitis. However, among them, the less invasive therapies are usually ineffective, whereas the invasive ones carry potential risks of serious side effects and complications. Pulsed radiofrequency (PRF) treatment of the superior hypogastric plexus may be an alternative to conventional treatments, as it provides nondestructive neuromodulation to the superior hypogastric plexus, which transmits the majority of pain signals from the pelvic viscera. Patient concerns: For 7 years, a 35-year-old female patient had been experiencing lo...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
CONCLUSIONS: Our findings indicate a role of the TACR1 gene in the development of sicca syndrome in subjects affected with FM. PMID: 25786041 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
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