Glycolipid-Mediated Basophil Activation in Alpha-Gal Allergy

Alpha-gal-containing glycolipids activate basophils sensitized with plasma from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for glycolipid in the effector phase of IgE-mediated food allergy.

Source: Journal of Allergy and Clinical Immunology - February 19, 2020 Category: Allergy & Immunology Authors: Onyinye I. Iweala, Shailesh K. Choudhary, Claire T. Addison, Cole J. Batty, Camille M. Kapita, Claire Amelio, Alexander J. Schuyler, Shenglou Deng, Eric M. Bachelder, Kristy M. Ainslie, Paul B. Savage, Patrick J. Brennan, Scott P. Commins Source Type: research